Neurodegenerative Diseases Modifying Therapies in AD and PD

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Frontier Pharma: Neurodegenerative Diseases - Protein Misfolding Targets and Neuromodulators Dominate the First-in-Class Pipeline and Lead the Way as Potential Disease-Modifying Therapies in AD and PD



Neurodegenerative diseases are becoming increasingly prevalent due to an aging population, but this diverse therapy area remains largely untreatable with current therapies. Neurodegenerative diseases are characterized by neuronal death in the brain and/or central nervous system (CNS), leading to the progressive decline in functional neurological capacities.

This report examines the entire neurodegenerative disease therapy area, with a particular focus on the three most prevalent neurodegenerative disorders: Alzheimer’s disease (AD), Parkinson’s disease (PD) and multiple sclerosis (MS).

AD and PD represent the most pressing challenges within the disease cluster, due to rapidly increasing prevalence driven by aging populations.

MS, the autoimmune disease of the CNS, contrasts with the rest of this cluster, as it affects a different population demographics, and has a lucrative pharmacological market.

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