Approaching pain with an impulse!
The Pain Drug Development Market report provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for Osteoarthritis Pain, Migraine pain and Neuropathic Pain, therefore covering a number of the most difficult-to-treat chronic and acute pain subtypes.
Report Study
The size of these pipelines ranges from 62 products in osteoarthritis pain to 249 in neuropathic pain. Within osteoarthritis pain, prostaglandin G/H synthases 1 and 2 and the nerve growth factor receptors are being studied by the most pipeline products; while the prostaglandin receptors are frequently targeted by already approved marketed products, the nerve growth factor receptors are not.
In migraine, it is the 5-hydroxytryptamine (serotonin) receptors 1D and 1B which are being most frequently studied, again reflecting the composition of the market for this indication. However, the calcitonin gene related peptide and its receptor, also very frequently targeted, are not yet present in the migraine market. Finally, the favoured targets of neuropathic pain are the sodium channel protein type 9 (Nav1.9) and the mu type opioid receptor. While the latter is already heavily targeted in the pain market, the former is not.
The size of these pipelines ranges from 62 products in osteoarthritis pain to 249 in neuropathic pain. Within osteoarthritis pain, prostaglandin G/H synthases 1 and 2 and the nerve growth factor receptors are being studied by the most pipeline products; while the prostaglandin receptors are frequently targeted by already approved marketed products, the nerve growth factor receptors are not.
In migraine, it is the 5-hydroxytryptamine (serotonin) receptors 1D and 1B which are being most frequently studied, again reflecting the composition of the market for this indication. However, the calcitonin gene related peptide and its receptor, also very frequently targeted, are not yet present in the migraine market. Finally, the favoured targets of neuropathic pain are the sodium channel protein type 9 (Nav1.9) and the mu type opioid receptor. While the latter is already heavily targeted in the pain market, the former is not.
Key Players
·
Osteoarthritis Pain
·
Migraine pain
·
Neuropathic Pain
Osteoarthritis Pain
-
Osteoarthritis pain is the most common symptom associated
with osteoarthritis which causes disruption of the cartilage.
-
This further leads to rubbing of the bones against each
other stimulating pain.
Migraine pain
-
Migraine is a disorder characterized by repeated attacks of
severe headache.
-
A migraine headache causes throbbing or pulsating pain,
usually on only one side of the head.
-
These headaches are often associated with nausea, vomiting,
and extreme sensitivity to light and sound.
Neuropathic Pain
-
Neuropathic pain, or neuralgia, is a condition in which the
sensory system is affected.
-
It is commonly accompanied by tissue injury, in which the
nerve fibres could be damaged resulting in the generation of abnormal
signals.
Scope
-
Which companies are the most active within the pipeline for
pain therapeutics?
-
Which pharmaceutical approaches are the most prominent at
each stage of the pipeline and within each indication?
-
To what extent do universities and institutions play a role
within this pipeline, compared to pharmaceutical companies?
-
What are the most important R&D milestones and data
publications to have happened in the field of pain therapeutics?
Reasons to buy
-
Understand the overall pipeline, with an at-a-glance overview
of all products in therapeutic development for each indication
-
Assess the products in development in granular detail, with
an up-to-date overview of each individual pipeline program in each indication,
and a comprehensive picture of recent updates and milestones for each
-
Analyze the companies, institutions and universities
currently operating in the pipeline, and the products being fielded by each of
these
-
Understand the composition of the pipeline in terms of
molecule type, molecular target, mechanism of action and route of
administration
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